Presentation:
Paint 15ml. Phial
Ointment 20 gm. Tube.

Composition :
CREAM : Clotrimazole I.P. 1%
LOTION : Clotrimazole I.P. 1%

Action & Use :
Clotrimazole is a broad –spectrum Antifungal Drug for topical use. It is also active against yeast and dermatophytes. It alters permeability of fungal cell wall through inhibition of ergosterol synthesis. It has a very little systemic absorption yet it penetrates the epidermic layer and thereby prompt action is assured.

Indication :
It is effective in wide range of Fungi like Tinea Cruris, Tinea Barbae, Tinea Corporis, Pityriasis Versicolor, Tinea Capitis, Tinea Pedis, Paronychia , Fungal Nappy Rash, Candidiasis or any other superficial fungal infection.

Mode of Application :
The preparations to be applied 2 to 3 times daily and to be continued 2 weeks more after disappearance of the symptoms of total eradication of the infection.

Presentation :
CLOMAZOLE CREAM – 15 gm Tube
CLOMAZOLE LOTION – 15 ml. Phial

Presentation :
100 ml phial.

Composition :
Zinc Sulphate I.P 4% w/v
Postassium Sulphurate B P C 4% w/v
Sodium Thiosulphate I.P 1% w/v

Action and Uses :
The blemishes on the face and trunk are often caused by fungal infection e.g. Pityrosporum ovale Pityrosporum furfur and whereas acne is a bacterial infection.

Sulphur is known to possess antiseptic properties when used locally. For this reason sulphur has been found to be effective in controlling acne and other parasitic infection. Lotion of Potassium Sulphurate is used in acne, eczema, often prescribed with Zinc Sulphate as a lotion for skin diseases. This produces nascent Hydrogen Sulphide which rapidly kills pityrosporum ovale , the causative fungus of seborrhoeic dermatitis and P. furfur Higher concentration of both the salt helps act particularly in refractory conditions.

Sodium Thiosulphate is also a sulphur containing salt. This also helps to improve the action of other Sulphur containing salts and thus the infections caused by the fungi are promptly controlled.

Indications :
Seborrhoeic Dermatitis Acne vulgaris and Pityriasis versicolor. It is also very useful for refractory conditions.

Mode of Application :
The lotion is to be applied with a cotton or sponge twice daily on the affected parts till the affected areas are free from infection. In case there is depigmentation Thiotar Ointment is to be applied on the affected part at bed time to restore the normal colour of the skin.

Presentation :
60 ml Phial.

Composition :
Basic Fuchsin B.P.C. 1%
Carbolic Acid I.P. 5%
Boric Acid I.P. 1%
Resorcin I.P. 10%
Acetone B.P.C’ 68 5%
Phenyl Mercuric Nitrate I.P 0.1%
Alcohol I.P. 10%

Causative Organism :
Ringworm of the nail (T. Unguim), interdigital ringworm (Tinea pedis,Tinea interdigitale) commonly know as Bengal Rot, Mango toe. athlete’s foot, are the most intractable condition which often recur frequently. These diseases are caused by Trichophyton rubrum. T. mentagrophytes. Epidermophyton floccosum.
Common medicines cannot penetrate sufficiently so as to render the fungicidal action of the drug. On the other hand Castellani’s Paint can penetrate into the deeper layer and effectively control those infections as this preparation is specific against interdigital ringworm and ringworm of the nail.

Action and Use :
Boric Acid has got Bacterio-static, Fungistatic & Astringent properties & is also an emulsifier.
Carbolic Acid is an Antiseptic & Disinfectant agent. It has Bactericidal action and removes itching.
Resorcin is Antipruritic , Antifungal and Keratolytic agent and effective in seborrhoeic dermatitis.
Basic Fuchsin is effective against grampositive bacteria & some dermatophytoses & also effective in impetigo.
Phenyl Mercuric Nitrate has antibacterial and anti fungul Properties.
Acetone as a solvent takes care of inflammatory conditions.

Indication :
Tinea Infections – Nail Fungus- Intedigital Rigworm.
It is indicated specially in Tinea unguium and also in Tinea infections of all kinds including refractory tinea infections.

Mode of Application :
The affected part of the nail is to be scrapped thoroughly and the paint is to be applied twice daily till the infection disappears completely.

Presentation:
20 ml phial.

PAINT
Composition :
Each Tablet contains
Fluconazole: 150 mg.

ACTION & USE :
Fluconazole is a bis-triazole antifungal drug and is structurally related to imidazole derivatives. It is fungistatic in action and exerts its antifungal activity by altering cellular membranes resulting in increased membrane permeability, leakage of essential elements and impaired uptake of precursor molecules of DNA. It is used as a systemic broadspectrum anti- fungal and highly effective against both yeasts and molds with minimum side effect.

INDICATION :
Floret is a broad spectrum antifungal agent administered by mouth.
It is indicated in:
= Superficial mucosal candidiasis & for any other fungal skin infections.
= Systemic fungal infections including systemic candidiasis.
= Coccidiosis
= Cryptococcosis.
= Blastomycosis and chromoblastomycosis.
= Histoplasmosis.
= Vaginal candidiasis.
= Anti-fungal treatment of AIDS Patients.

DOSES :
Candidiasis- floret- 150 mg 1 tablet weekly for1 to 2 weeks.
Pityriasis versicolor- 400 mg- 400 mg , single dose, or 150 mg 1 tablet for 4-6 weeks.
Paronychia or Onychomycosis- 150 mg 1 tablet weekly for 6-12 months.
Tinea infections: 150 mg 1 tablet weekly for 4-6 weeks.
Oropharyngial candidiasis- 150 mg – 200mg. 1 tablet daily for 2 weeks.
AIDS related fungal infections- 150 mg – 200 mg, 1 tablet daily for 2-3 weeks.

PRESENTATIONS :
1 tablet of floret 150 in a box.

Composition :
Clotrimazole I.P. 1% w/v
Propylene Glycol I.P.
Glycerin I.P. base q.s.

Action & Use :
Clotrimazole is a broad –spectrum Antifungal Drug for topical use. It is also active against yeast and dermatophytes. It alters permeability of fungal cell wall through inhibition of ergosterol synthesis. It has a very little systemic absorption yet it penetrates the epidermic layer and thereby prompt action is assured.

Indication :
It is effective in wide range of Fungi including Tinea infections and for the treatment of Oropharyngeal Candidiasis and other fungal infections of the oral cavity.

Mode of Application :
Apply 5 to 10 drops to cover all the lesions in the mouth, preferably with a cotton bud, 3 to 4 times a day.

Presentation :
15 ml. Phial